Graeme Semple, Ph.D.

Vice President, Chemistry

Graeme Semple has more than 26 years of drug discovery experience in the pharmaceutical industry, both in biotech and big pharma, most recently at Arena Pharmaceuticals where he was VP of Discovery Chemistry and oversaw medicinal chemistry and early development projects.  More than a dozen of these projects delivered candidates into preclinical and clinical development in the areas of Metabolism, CNS, Inflammation and Cardiovascular disease. Prior to Arena, he was a Disease Area Chemist at AstraZeneca, Mölndal, Sweden, where he initiated a number of early stage medicinal chemistry projects in the GI area. Prior to AstraZeneca, he was Head of Chemistry at Ferring Research Institute, Southampton, U.K., where he led chemistry groups contributing to multi-national collaborative projects that delivered clinical candidates in the areas of cardiovascular, GI and urology. He is a co-inventor of the GnRH antagonist drug Firmagon ® (Degarelix) which has been approved in 74 countries. He was a post-doctoral fellow at the Universities of Bath and Oxford, UK and has a Ph.D. in Chemistry from the University of Warwick, UK.